Issue 7, 2004

Solvent-drop grinding: green polymorph control of cocrystallisation

Abstract

By grinding with a minimal addition of a solvent of appropriate polarity, control over the polymorphic outcome of a novel cocrystallisation involving the model pharmaceutical compound caffeine may be achieved.

Graphical abstract: Solvent-drop grinding: green polymorph control of cocrystallisation

Supplementary files

Article information

Article type
Communication
Submitted
21 Jan 2004
Accepted
20 Feb 2004
First published
05 Mar 2004

Chem. Commun., 2004, 890-891

Solvent-drop grinding: green polymorph control of cocrystallisation

A. V. Trask, W. D. S. Motherwell and W. Jones, Chem. Commun., 2004, 890 DOI: 10.1039/B400978A

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