Issue 10, 2004

Asymmetric synthesis of avenaciolide via cascade palladium catalysed cyclisation–carbonylation of bromodienes

Abstract

An asymmetric synthesis of the secondary metabolite avenaciolide has been achieved utilising a diastereoselective palladium catalysed cyclisation–carbonylation of bromodienes.

Graphical abstract: Asymmetric synthesis of avenaciolide via cascade palladium catalysed cyclisation–carbonylation of bromodienes

Supplementary files

Article information

Article type
Communication
Submitted
03 Mar 2004
Accepted
01 Apr 2004
First published
27 Apr 2004

Chem. Commun., 2004, 1232-1233

Asymmetric synthesis of avenaciolide via cascade palladium catalysed cyclisation–carbonylation of bromodienes

V. K. Aggarwal, P. W. Davies and A. T. Schmidt, Chem. Commun., 2004, 1232 DOI: 10.1039/B403183K

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