Recovery and recycle of fluoroalkyl-derivatised BINAP ligands using FRP silica gel

Abstract

Three chiral perfluoroalkylated bidentate phosphorus(III) ligands have been prepared and characterised. These ligands have been evaluated in the asymmetric hydrogenation of methyl acetoacetate in dichloromethane and compared with the parent, non-fluorinated, ruthenium catalyst systems. After catalysis, recovery and reuse of the ligands has been achieved.