Issue 2, 2005

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA

Abstract

Guanidine-based peptide nucleic acid (GPNA) with a D-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.

Graphical abstract: Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA

Supplementary files

Article information

Article type
Communication
Submitted
13 Aug 2004
Accepted
15 Oct 2004
First published
02 Dec 2004

Chem. Commun., 2005, 244-246

Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA

A. Dragulescu-Andrasi, P. Zhou, G. He and D. H. Ly, Chem. Commun., 2005, 244 DOI: 10.1039/B412522C

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