Issue 10, 2005
From the journal:

Chemical Communications

A pyrimidine-like nickel(ii) DNA base pair

Christopher Switzer*a  and  Dongwon Shina  

* Corresponding authors

a Department of Chemistry, University of California, Riverside, CA, USA
E-mail: switzer@citrus.ucr.edu
Fax: 951-827-4713
Tel: 951-827-7266

Abstract

4-(2′-Pyridyl)-pyrimidinone deoxyriboside is synthesized and characterized as a DNA metallo base-pair; this novel nucleoside forms a self-pair in the presence of Ni(II) and stabilizes double helical DNA to the same extent as a G·C pair.

Graphical abstract: A pyrimidine-like nickel(ii) DNA base pair

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Article information

DOI
https://doi.org/10.1039/B415426F
Article type
Communication
Submitted
05 Oct 2004
Accepted
12 Nov 2004
First published
19 Jan 2005

Chem. Commun., 2005, 1342-1344

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A pyrimidine-like nickel(II) DNA base pair

C. Switzer and D. Shin, Chem. Commun., 2005, 1342 DOI: 10.1039/B415426F

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