Issue 17, 2005

Synthesis and anti-cancer activity of dinuclear platinum(ii) complexes containing bis(thioalkyl)dicarba-closo-dodecaborane(12) ligands

Abstract

A series of novel, dinuclear (2,2′:6′,2″-terpyridine)platinum(II) complexes containing bis(thioalkyl)-dicarba-closo-dodecaborane(12) (carborane) ligands were prepared and characterised, and their preliminary anti-cancer characteristics have been determined in vitro; the complexes are the first examples of bis-intercalator complexes containing a boron-rich carborane cage.

Graphical abstract: Synthesis and anti-cancer activity of dinuclear platinum(ii) complexes containing bis(thioalkyl)dicarba-closo-dodecaborane(12) ligands

Supplementary files

Article information

Article type
Communication
Submitted
14 Jun 2005
Accepted
12 Jul 2005
First published
25 Jul 2005

Dalton Trans., 2005, 2827-2829

Synthesis and anti-cancer activity of dinuclear platinum(II) complexes containing bis(thioalkyl)dicarba-closo-dodecaborane(12) ligands

S. L. Woodhouse, E. J. Ziolkowski and L. M. Rendina, Dalton Trans., 2005, 2827 DOI: 10.1039/B508340K

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