Issue 45, 2005
From the journal:

Chemical Communications

Solid phase synthesis of a spiro[5.5]ketal library†

Stefan Sommerab  and  Herbert Waldmannab  

a Max-Planck Institute of Molecular Physiology, Otto-Hahn-Str. 11, Dortmund, Germany
E-mail: herbert.waldmann@mpi-dortmund.mpg.de

b Department of Chemical Biology, University of Dortmund, Otto-Hahn-Str. 6, Dortmund, Germany
E-mail: herbert.waldmann@mpi-dortmund.mpg.de

Abstract

A spiro[5.5]ketal library embodying the core structure of numerous biologically active natural products was synthesized employing a double intramolecular hetero Michael reaction as a key transformation.

Graphical abstract: Solid phase synthesis of a spiro[5.5]ketal library

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Article information

DOI
https://doi.org/10.1039/B511177C
Article type
Communication
Submitted
04 Aug 2005
Accepted
16 Sep 2005
First published
19 Oct 2005

Chem. Commun., 2005, 5684-5686

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Solid phase synthesis of a spiro[5.5]ketal library

S. Sommer and H. Waldmann, Chem. Commun., 2005, 5684 DOI: 10.1039/B511177C

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