Issue 47, 2005
From the journal:

Chemical Communications

Reduction of alkynes into 1,2-dideuterioalkenes with hexamethyldisilane and deuterium oxide in the presence of a palladium catalyst†

Eiji Shirakawa,*a   Hidehito Otsukaa  and  Tamio Hayashi*a  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Japan
E-mail: shirakawa@kuchem.kyoto-u.ac.jp
Fax: 81 75 753 3988

Abstract

A combination of hexamethyldisilane and deuterium oxide was found to work as a deuterium transfer reagent for alkynes in the presence of a catalytic amount of a palladium complex to give (E)-1,2-dideuterioalkenes selectively through the corresponding (Z)-isomer.

Graphical abstract: Reduction of alkynes into 1,2-dideuterioalkenes with hexamethyldisilane and deuterium oxide in the presence of a palladium catalyst

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Article information

DOI
https://doi.org/10.1039/B512245G
Article type
Communication
Submitted
05 Sep 2005
Accepted
05 Oct 2005
First published
02 Nov 2005

Chem. Commun., 2005, 5885-5886

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Reduction of alkynes into 1,2-dideuterioalkenes with hexamethyldisilane and deuterium oxide in the presence of a palladium catalyst

E. Shirakawa, H. Otsuka and T. Hayashi, Chem. Commun., 2005, 5885 DOI: 10.1039/B512245G

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