Issue 22, 2006

The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's β-amyloid polypeptide

Abstract

Alzheimer's β-amyloid diphenylalanine motif has previously been shown to self-assemble into discrete and extraordinary stiff nanotubes; these nanotubes were initially thought to be distinct from the single crystal structure of diphenylalanine, but it is now shown that the X-ray powder diffraction pattern of the nanotubes is identical to the simulated pattern for the single crystal structure, affording a new foundation for understanding and rationalizing the properties of this remarkable organic material.

Graphical abstract: The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's β-amyloid polypeptide

Supplementary files

Article information

Article type
Communication
Submitted
01 Mar 2006
Accepted
30 Mar 2006
First published
13 Apr 2006

Chem. Commun., 2006, 2332-2334

The structure of nanotubes formed by diphenylalanine, the core recognition motif of Alzheimer's β-amyloid polypeptide

C. H. Görbitz, Chem. Commun., 2006, 2332 DOI: 10.1039/B603080G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements