Issue 32, 2006
From the journal:

Chemical Communications

Stereoselective synthesis of highly O-functionalized enantiopure 2,3,4-trisubstituted tetrahydrofurans by tandem debenzylative cyclization of glycal derived 2,3-epoxy alcohols†‡

L. Vijaya Raghava Reddy,a   Abhijeet Deb Roy,b   Raja Royb  and  Arun K. Shaw*a  

* Corresponding authors

a Division of Medicinal and Process Chemistry, Central Drug Research Institute (CDRI), Lucknow 226001, India
E-mail: akshaw55@yahoo.com

b Division of Sophisticated Analytical Instrumentation Facility, Central Drug Research Institute(CDRI), Lucknow 226001, India
E-mail: rajaroy_cdri@yahoo.com

Abstract

A new and highly efficient methodology for the construction of synthetically important highly O-functionalized enantiopure 2,3,4-trisubstituted tetrahydrofurans with three contiguous stereocenters is reported.

Graphical abstract: Stereoselective synthesis of highly O-functionalized enantiopure 2,3,4-trisubstituted tetrahydrofurans by tandem debenzylative cyclization of glycal derived 2,3-epoxy alcohols

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Article information

DOI
https://doi.org/10.1039/B606519H
Article type
Communication
Submitted
09 May 2006
Accepted
13 Jun 2006
First published
10 Jul 2006

Chem. Commun., 2006, 3444-3446

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Stereoselective synthesis of highly O-functionalized enantiopure 2,3,4-trisubstituted tetrahydrofurans by tandem debenzylative cyclization of glycal derived 2,3-epoxy alcohols

L. V. R. Reddy, A. D. Roy, R. Roy and A. K. Shaw, Chem. Commun., 2006, 3444 DOI: 10.1039/B606519H

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