Issue 37, 2006

Effects of reaction rate of radical anion of a photosensitizer with molecular oxygen on the photosensitized DNA damage

Abstract

Based on the synthesis of DNA modified with photosensitizers, direct spectroscopic measurements of the hole transfer in DNA, and quantification of the yield of the DNA oxidative damage, the reaction rate of the radical anion of the photosensitizer was demonstrated to be critically important in determining the efficiency of photosensitized DNA damage.

Graphical abstract: Effects of reaction rate of radical anion of a photosensitizer with molecular oxygen on the photosensitized DNA damage

Article information

Article type
Communication
Submitted
06 Jun 2006
Accepted
04 Jul 2006
First published
07 Aug 2006

Chem. Commun., 2006, 3918-3920

Effects of reaction rate of radical anion of a photosensitizer with molecular oxygen on the photosensitized DNA damage

K. Kawai, Y. Osakada, M. Fujitsuka and T. Majima, Chem. Commun., 2006, 3918 DOI: 10.1039/B608027H

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