Issue 2, 2007
From the journal:

Green Chemistry

Solvent-free one-pot four-component synthesis of 2-aminomorpholines. Access to related diaminoalcohols†

Thomas Régnier,a   Fabienne Berrée,*a   Olivier Lavastrea  and  Bertrand Carbonia  

* Corresponding authors

a Sciences Chimiques de Rennes, UMR 6226 CNRS-Université de Rennes 1, Bat 10 A, Campus de Beaulieu, Rennes Cedex, France
E-mail: fabienne.berree@univ-rennes1.fr
Fax: (33) 0223236227
Tel: (33) 0223235735

Abstract

Under microwave irradiation, a series of 2-aminomorpholines were readily produced in a straightforward four-component process from commercially available 1,2-aminoalcohols, glyoxal, boronic acids and aliphatic or aromatic amines. Further reduction furnished the corresponding diaminoalcohols.

Graphical abstract: Solvent-free one-pot four-component synthesis of 2-aminomorpholines. Access to related diaminoalcohols

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Article information

DOI
https://doi.org/10.1039/B613395A
Article type
Communication
Submitted
14 Sep 2006
Accepted
19 Dec 2006
First published
22 Dec 2006

Green Chem., 2007,9, 125-126

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Solvent-free one-pot four-component synthesis of 2-aminomorpholines. Access to related diaminoalcohols

T. Régnier, F. Berrée, O. Lavastre and B. Carboni, Green Chem., 2007, 9, 125 DOI: 10.1039/B613395A

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