Issue 12, 2007
From the journal:

Chemical Communications

Polymeric model systems for flavoenzyme activity: towards synthetic flavoenzymes†

Brian J. Jordan,a   Graeme Cooke,*b   James F. Garety,b   Michael A. Pollier,a   Nadiya Kryvokhyzha,b   Ali Bayir,a   Gouher Rabanib  and  Vincent M. Rotelloa  

* Corresponding authors

a Department of Chemistry, University of Massachusetts at Amherst, Amherst, MA 01003, USA

b WestCHEM, Department of Chemistry, Joseph Black Building, University of Glasgow, Glasgow, UK
E-mail: graemec@chem.gla.ac.uk

Abstract

We report the synthesis of a water-soluble flavin polymer using ATRP, whereby the oligoethylene glycol backbone provides both a local hydrophobic environment and redox tuning of the flavin moiety typical of flavoenzyme prototypes.

Graphical abstract: Polymeric model systems for flavoenzyme activity: towards synthetic flavoenzymes

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Article information

DOI
https://doi.org/10.1039/B616159F
Article type
Communication
Submitted
07 Nov 2006
Accepted
06 Dec 2006
First published
18 Dec 2006

Chem. Commun., 2007, 1248-1250

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Polymeric model systems for flavoenzyme activity: towards synthetic flavoenzymes

B. J. Jordan, G. Cooke, J. F. Garety, M. A. Pollier, N. Kryvokhyzha, A. Bayir, G. Rabani and V. M. Rotello, Chem. Commun., 2007, 1248 DOI: 10.1039/B616159F

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