Issue 22, 2007
From the journal:

Chemical Communications

Sugar sensing based on induced pH changes

Youngmi Kim,a   Scott A. Hilderbrand,a   Ralph Weissledera  and  Ching-Hsuan Tung*a  

* Corresponding authors

a Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
E-mail: tung@helix.mgh.harvard.edu
Fax: +1 617 726 5708
Tel: +1 617 726 5779

Abstract

A sensory assembly consisting of a pH sensitive NIR dye and an arylboronic acid shows ratiometric absorption changes with increased fluorescence intensity upon addition of sugar in aqueous media; this demonstrates a new signal transduction mechanism for the detection of sugar based on pH changes induced in the microenvironment of the sensory assembly.

Graphical abstract: Sugar sensing based on induced pH changes

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Article information

DOI
https://doi.org/10.1039/B700741H
Article type
Communication
Submitted
17 Jan 2007
Accepted
15 Feb 2007
First published
09 Mar 2007

Chem. Commun., 2007, 2299-2301

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Sugar sensing based on induced pH changes

Y. Kim, S. A. Hilderbrand, R. Weissleder and C. Tung, Chem. Commun., 2007, 2299 DOI: 10.1039/B700741H

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