Issue 30, 2007

Iron sulfur cluster biosynthesis. Human NFU mediates sulfide delivery to ISU in the final step of [2Fe–2S] cluster assembly

Abstract

Human NFU forms a complex with NifS-like proteins and is a functionally competent reducing agent for cysteinyl persulfide bond cleavage, releasing inorganic sulfide for incorporation into the ISU-bound [2Fe–2S] cluster.

Graphical abstract: Iron sulfur cluster biosynthesis. Human NFU mediates sulfide delivery to ISU in the final step of [2Fe–2S] cluster assembly

Supplementary files

Article information

Article type
Communication
Submitted
03 Apr 2007
Accepted
10 May 2007
First published
06 Jun 2007

Chem. Commun., 2007, 3192-3194

Iron sulfur cluster biosynthesis. Human NFU mediates sulfide delivery to ISU in the final step of [2Fe–2S] cluster assembly

Y. Liu and J. A. Cowan, Chem. Commun., 2007, 3192 DOI: 10.1039/B704928E

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