Issue 5, 2008
From the journal:

Chemical Society Reviews

SERS—a single-molecule and nanoscale tool for bioanalytics

Janina Kneipp,*ab   Harald Kneippa  and  Katrin Kneippac  

* Corresponding authors

a Harvard University Medical School, Wellman Center for Photomedicine, Boston, USA
E-mail: kneipp@usa.net

b Federal Institute for Materials Research and Testing, Berlin, Germany
E-mail: jkneipp@janina-kneipp.de

c Harvard-MIT Division of Health Sciences and Technology, Cambridge, USA

Abstract

Surface enhanced Raman scattering (SERS) at extremely high enhancement level turns the weak inelastic scattering effect of photons on vibrational quantum states into a structurally sensitive single-molecule and nanoscale probe. The effect opens up exciting opportunities for applications of vibrational spectroscopy in biology. The concept of SERS can be extended to two-photon excitation by exploiting surface enhanced hyper-Raman scattering (SEHRS). This critical review introduces the physics behind single-molecule SERS and discusses the capabilities of the effect in bioanalytics (100 references).

Graphical abstract: SERS—a single-molecule and nanoscale tool for bioanalytics

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B708459P
Article type
Critical Review
Submitted
13 Mar 2008
First published
20 Mar 2008

Chem. Soc. Rev., 2008,37, 1052-1060

Permissions

Request permissions

SERS—a single-molecule and nanoscale tool for bioanalytics

J. Kneipp, H. Kneipp and K. Kneipp, Chem. Soc. Rev., 2008, 37, 1052 DOI: 10.1039/B708459P

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements