Issue 6, 2007

Structural biology in plant natural product biosynthesis—architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis

Abstract

Covering: 1997 to 2007

Several cDNAs of enzymes catalyzing biosynthetic pathways of plant-derived alkaloids have recently been heterologously expressed, and the production of appropriate enzymes from ajmaline and tropane alkaloid biosynthesis in bacteria allows their crystallization. This review describes the architecture of these enzymes with and without their ligands.

Graphical abstract: Structural biology in plant natural product biosynthesis—architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis

Article information

Article type
Review Article
Submitted
02 Aug 2007
First published
24 Oct 2007

Nat. Prod. Rep., 2007,24, 1382-1400

Structural biology in plant natural product biosynthesis—architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis

J. Stöckigt and S. Panjikar, Nat. Prod. Rep., 2007, 24, 1382 DOI: 10.1039/B711935F

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