Aerobic oxidation of aldehydes under ambient conditions using supported gold nanoparticle catalysts

Abstract

A new, green protocol for producing simple esters by selectively oxidizing an aldehyde dissolved in a primary alcohol has been established, utilising air as the oxidant and supported gold nanoparticles as catalyst. The oxidative esterifications proceed with excellent selectivities at ambient conditions; the reactions can be performed in an open flask and at room temperature. Benzaldehyde is even oxidised at a reasonable rate below −70 °C. Acrolein is oxidised to methyl acrylate in high yield using the same protocol.