Issue 47, 2007

Bicyclic guanidine-catalyzed enantioselective phospha-Michael reaction: synthesis of chiral β-aminophosphine oxides and β-aminophosphines

Abstract

Chiral bicyclic guanidine has been found to catalyze the phospha-Michael reactions of diaryl phosphine oxide to nitroalkenes with high enantioselectivities, offering a direct methodology to prepare chiral β-aminophosphine oxides and β-aminophosphines.

Graphical abstract: Bicyclic guanidine-catalyzed enantioselective phospha-Michael reaction: synthesis of chiral β-aminophosphine oxides and β-aminophosphines

Supplementary files

Article information

Article type
Communication
Submitted
28 Aug 2007
Accepted
20 Sep 2007
First published
01 Oct 2007

Chem. Commun., 2007, 5058-5060

Bicyclic guanidine-catalyzed enantioselective phospha-Michael reaction: synthesis of chiral β-aminophosphine oxides and β-aminophosphines

X. Fu, Z. Jiang and C. Tan, Chem. Commun., 2007, 5058 DOI: 10.1039/B713151H

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