Issue 21, 2008
From the journal:

Dalton Transactions

Water-soluble cyclodiphosphazanes: synthesis, gold(i) metal complexes and their in vitro antitumor studies†

D. Suresh,a   Maravanji S. Balakrishna,*a   Krishnan Rathinasamy,b   Dulal Panda*b  and  Shaikh M. Mobinc  

* Corresponding authors

a Phosphorus Laboratory, Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, India
E-mail: krishna@chem.iitb.ac.in
Fax: +91-22-2576-7152

b School of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India
E-mail: panda@btc.iitb.ac.in
Fax: +91-22-2572-3480

c National Single Crystal X-ray Diffraction Facility, Indian Institute of Technology Bombay, Mumbai, India

Abstract

The newly synthesized water-soluble cyclodiphosphazane ligands and their gold(I) complexes inhibit HeLa cell proliferation by activating p53 protein and inducing apoptosis.

Graphical abstract: Water-soluble cyclodiphosphazanes: synthesis, gold(i) metal complexes and their in vitro antitumor studies

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Article information

DOI
https://doi.org/10.1039/B804026P
Article type
Communication
Submitted
07 Mar 2008
Accepted
17 Mar 2008
First published
01 Apr 2008

Dalton Trans., 2008, 2812-2814

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Water-soluble cyclodiphosphazanes: synthesis, gold(I) metal complexes and their in vitro antitumor studies

D. Suresh, M. S. Balakrishna, K. Rathinasamy, D. Panda and S. M. Mobin, Dalton Trans., 2008, 2812 DOI: 10.1039/B804026P

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