Issue 31, 2008

Salt-induced guest relocation from a macrocyclic cavity into a biomolecular pocket: interplay between cucurbit[7]uril and albumin

Abstract

The binding affinity of Neutral Red with cucurbit[7]uril (CB7) can be fine-tuned by addition and competitive binding of metal ions, which leads also to a pKa shift of the dye; this can be exploited to relocate the dye from the macrocyclic cavity of CB7 to the biomolecular pocket of bovine serum albumin.

Graphical abstract: Salt-induced guest relocation from a macrocyclic cavity into a biomolecular pocket: interplay between cucurbit[7]uril and albumin

Supplementary files

Article information

Article type
Communication
Submitted
14 Mar 2008
Accepted
30 Apr 2008
First published
12 Jun 2008

Chem. Commun., 2008, 3681-3683

Salt-induced guest relocation from a macrocyclic cavity into a biomolecular pocket: interplay between cucurbit[7]uril and albumin

M. Shaikh, J. Mohanty, A. C. Bhasikuttan, V. D. Uzunova, W. M. Nau and H. Pal, Chem. Commun., 2008, 3681 DOI: 10.1039/B804381G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements