Issue 9, 2008

Improved chemoselective, ecofriendly conditions for the conversion of primary alkyl halides into nitroalkanes under PEG400

Abstract

Treatment of primary alkyl bromides or iodides with 1.5–3 equivalents of sodium nitrite, at room temperature, in PEG400 as solvent, allows the chemoselective formation of primary nitroalkanes in satisfactory to good yields, under ecofriendly reaction conditions.

Graphical abstract: Improved chemoselective, ecofriendly conditions for the conversion of primary alkyl halides into nitroalkanes under PEG400

Article information

Article type
Paper
Submitted
08 Apr 2008
Accepted
18 Jun 2008
First published
11 Aug 2008

Green Chem., 2008,10, 1004-1006

Improved chemoselective, ecofriendly conditions for the conversion of primary alkyl halides into nitroalkanes under PEG400

R. Ballini, L. Barboni and A. Palmieri, Green Chem., 2008, 10, 1004 DOI: 10.1039/B805985C

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