Issue 21, 2009
From the journal:

Chemical Communications

Molecular beacon-functionalized gold nanoparticles as probes in dry-reagent strip biosensor for DNA analysis†

Xun Mao,ab   Hui Xu,b   Qingxiang Zeng,b   Lingwen Zeng*a  and  Guodong Liu*b  

* Corresponding authors

a Laboratory of Molecular Diagnostics, Guangzhou Institute of Biomedicine and Health, Chinese academy of Sciences, Guangzhou, Guangdong, China
E-mail: zeng6@yahoo.com

b Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, USA
E-mail: guodong.liu@ndsu.edu
Fax: 1-701-231-8831
Tel: 1-701-231-8697

Abstract

The highly specific molecule recognition properties of molecular beacons (MB) are combined with the unique optical properties of gold nanoparticles (Au-NPs) for the development of a dry-reagent strip-type nucleic acidbiosensor (DSNAB) that enables sensitive and low-cost detection of nucleic acid samples within 15 min.

Graphical abstract: Molecular beacon-functionalized gold nanoparticles as probes in dry-reagent strip biosensor for DNA analysis

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Article information

DOI
https://doi.org/10.1039/B822582F
Article type
Communication
Submitted
17 Dec 2008
Accepted
19 Mar 2009
First published
15 Apr 2009

Chem. Commun., 2009, 3065-3067

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Molecular beacon-functionalized gold nanoparticles as probes in dry-reagent strip biosensor for DNA analysis

X. Mao, H. Xu, Q. Zeng, L. Zeng and G. Liu, Chem. Commun., 2009, 3065 DOI: 10.1039/B822582F

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