Issue 8, 2009
From the journal:

Organic & Biomolecular Chemistry

π-Activated alcohols: an emerging class of alkylating agents for catalytic Friedel–Crafts reactions

Marco Bandini*a  and  Michele Tragnia  

* Corresponding authors

a Dipartimento di Chimica “G. Ciamician”, - Alma Mater Studiorum - Università di Bologna, via Selmi 2, Bologna, Italy
E-mail: marco.bandini@unibo.it
Fax: +39-051-2099456
Tel: +39-051-2099751

Abstract

The direct functionalization of aromatic compounds, via Friedel–Crafts alkylation reactions with alcohols, is one of the cornerstones in organic chemistry. The present emerging area deals with the recent advances in the use of π-activated alcohols in the catalytic and stereoselective construction of benzylic stereocenters.

Graphical abstract: π-Activated alcohols: an emerging class of alkylating agents for catalytic Friedel–Crafts reactions

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Article information

DOI
https://doi.org/10.1039/B823217B
Article type
Emerging Area
Submitted
05 Jan 2009
Accepted
23 Jan 2009
First published
02 Mar 2009

Org. Biomol. Chem., 2009,7, 1501-1507

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π-Activated alcohols: an emerging class of alkylating agents for catalytic Friedel–Crafts reactions

M. Bandini and M. Tragni, Org. Biomol. Chem., 2009, 7, 1501 DOI: 10.1039/B823217B

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