Issue 20, 2009

Concise total synthesis of (±)-aspidospermidinevia an oxidative Hosomi–Sakurai process

Abstract

A concise total synthesis of (±)-aspidospermidine has been achieved in twelve steps from inexpensive 4-ethylphenol, based on an oxidative Hosomi–Sakurai reaction via the concept of “aromatic ring umpolung”.

Graphical abstract: Concise total synthesis of (±)-aspidospermidinevia an oxidative Hosomi–Sakurai process

Supplementary files

Article information

Article type
Communication
Submitted
19 Feb 2009
Accepted
14 Apr 2009
First published
27 Apr 2009

Chem. Commun., 2009, 2941-2943

Concise total synthesis of (±)-aspidospermidinevia an oxidative Hosomi–Sakurai process

C. Sabot, K. C. Guérard and S. Canesi, Chem. Commun., 2009, 2941 DOI: 10.1039/B903530C

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