Issue 12, 2009

A hydrophilic three side-chained triazatruxene as a new strong and selective G-quadruplex ligand

Abstract

A new hydrosoluble triazatruxene derivative (AZATRUX) is reported to selectively bind to G-quadruplex DNA, as derived by ESI-MS measurements and competition experiments.

Graphical abstract: A hydrophilic three side-chained triazatruxene as a new strong and selective G-quadruplex ligand

Supplementary files

Article information

Article type
Communication
Submitted
09 Mar 2009
Accepted
01 May 2009
First published
13 May 2009

Org. Biomol. Chem., 2009,7, 2513-2516

A hydrophilic three side-chained triazatruxene as a new strong and selective G-quadruplex ligand

L. Ginnari-Satriani, V. Casagrande, A. Bianco, G. Ortaggi and M. Franceschin, Org. Biomol. Chem., 2009, 7, 2513 DOI: 10.1039/B904723A

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