Issue 27, 2009

Copper-catalyzed aerobic phosphonation of sp3 C–H bonds

Abstract

An efficient cross-dehydrogenative-coupling (CDC) between sp3 C–H and H–P bonds was developed using copper salt as catalyst and molecular oxygen as terminal oxidant; this new methodology provides an easy access to biologically important α-aminophosphonates.

Graphical abstract: Copper-catalyzed aerobic phosphonation of sp3 C–H bonds

Supplementary files

Article information

Article type
Communication
Submitted
16 Mar 2009
Accepted
08 May 2009
First published
05 Jun 2009

Chem. Commun., 2009, 4124-4126

Copper-catalyzed aerobic phosphonation of sp3 C–H bonds

O. Baslé and C. Li, Chem. Commun., 2009, 4124 DOI: 10.1039/B905275E

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