Issue 32, 2009

Catalytic enantioselective conjugate addition of fluorobis(phenylsulfonyl)methane to enals: synthesis of chiral monofluoromethyl compounds

Abstract

A new highly catalytic enantioselective Michael addition of fluorobis(phenylsulfonyl)methane to α,β-unsaturated aldehydes has been developed for the preparation of chiral monofluoromethyl compounds under mild reaction conditions.

Graphical abstract: Catalytic enantioselective conjugate addition of fluorobis(phenylsulfonyl)methane to enals: synthesis of chiral monofluoromethyl compounds

Supplementary files

Article information

Article type
Communication
Submitted
14 Apr 2009
Accepted
22 Jun 2009
First published
13 Jul 2009

Chem. Commun., 2009, 4886-4888

Catalytic enantioselective conjugate addition of fluorobis(phenylsulfonyl)methane to enals: synthesis of chiral monofluoromethyl compounds

S. Zhang, Y. Zhang, Y. Ji, H. Li and W. Wang, Chem. Commun., 2009, 4886 DOI: 10.1039/B907399J

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