Issue 37, 2009
From the journal:

Chemical Communications

An ultrasensitive electrochemical “turn-on” label-free biosensor for Hg2+with AuNP-functionalized reporter DNA as a signal amplifier†

Rong-Mei Kong,a   Xiao-Bing Zhang,*a   Liang-Liang Zhang,a   Xiao-Yong Jin,a   Shuang-Yan Huan,a   Guo-Li Shena  and  Ru-Qin Yu*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, China
E-mail: xbzhang@hnu.cn, rqyu@hnu.cn
Fax: +86 731-8822782
Tel: +86 731-8822577

Abstract

A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on the strong and specific binding of Hg2+ by two DNAthymine bases (T–Hg2+–T) and the use of AuNP-functionalized reporter DNA to achieve signal amplification.

Graphical abstract: An ultrasensitive electrochemical “turn-on” label-free biosensor for Hg2+with AuNP-functionalized reporter DNA as a signal amplifier

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Article information

DOI
https://doi.org/10.1039/B911163H
Article type
Communication
Submitted
08 Jun 2009
Accepted
20 Jul 2009
First published
05 Aug 2009

Chem. Commun., 2009, 5633-5635

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An ultrasensitive electrochemical “turn-on” label-free biosensor for Hg2+with AuNP-functionalized reporter DNA as a signal amplifier

R. Kong, X. Zhang, L. Zhang, X. Jin, S. Huan, G. Shen and R. Yu, Chem. Commun., 2009, 5633 DOI: 10.1039/B911163H

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