Issue 41, 2009

Amide-based bifunctional organocatalysts in asymmetric reactions

Abstract

A series of amide-based bifunctional organocatalysts have been utilized in asymmetric reactions. Prolinamide analogues have been designed to catalyze asymmetric reactions via enamine intermediates with the assistance of tunable hydrogen bonding. In addition, the combination of various Lewis base functional groups, such as guanidine, N-oxide and phosphane, with an amide moiety have also constituted efficient bifunctional organocatalysts with unique reactivity and selectivity.

Graphical abstract: Amide-based bifunctional organocatalysts in asymmetric reactions

Article information

Article type
Feature Article
Submitted
06 Jul 2009
Accepted
11 Aug 2009
First published
27 Aug 2009

Chem. Commun., 2009, 6145-6158

Amide-based bifunctional organocatalysts in asymmetric reactions

X. Liu, L. Lin and X. Feng, Chem. Commun., 2009, 6145 DOI: 10.1039/B913411E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements