Issue 43, 2009
From the journal:

Chemical Communications

Effect of chirality of l/d-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(α-amino acid)-thymidine dimers†

Seema Bagmare,a   Moneesha D’Costaa  and  Vaijayanti A. Kumar*a  

* Corresponding authors

a Division of Organic Chemistry, National Chemical Laboratory, Pune 411008, India
E-mail: va.kumar@ncl.res.in
Fax: +91 20 25902629
Tel: +91 20 25902340

Abstract

The chirality of the amide linker in dimer blocks was found to have a profound effect on the orientation of base stacking interactions as studied by CD and NMR spectroscopy.

Graphical abstract: Effect of chirality of l/d-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(α-amino acid)-thymidine dimers

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Article information

DOI
https://doi.org/10.1039/B913546D
Article type
Communication
Submitted
07 Jul 2009
Accepted
08 Sep 2009
First published
25 Sep 2009

Chem. Commun., 2009, 6646-6648

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Effect of chirality of L/D-proline and prochiral glycine as the linker amino acid in five-atom linked thymidinyl-(α-amino acid)-thymidine dimers

S. Bagmare, M. D’Costa and V. A. Kumar, Chem. Commun., 2009, 6646 DOI: 10.1039/B913546D

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