Issue 6, 2010

Conversion of carbonyl compounds to alkynes: general overview and recent developments

Abstract

The preparation of alkynes from carbonyl compounds via a one-carbon homologation has become a very useful pathway for the synthesis of acetylenic compounds, both internal and terminal. This tutorial review provides an overview of the different methods available for this transformation, including their scope and limitations, recent developments and applications in total syntheses.

Graphical abstract: Conversion of carbonyl compounds to alkynes: general overview and recent developments

Article information

Article type
Tutorial Review
Submitted
30 Sep 2009
First published
24 Mar 2010

Chem. Soc. Rev., 2010,39, 2007-2017

Conversion of carbonyl compounds to alkynes: general overview and recent developments

D. Habrant, V. Rauhala and A. M. P. Koskinen, Chem. Soc. Rev., 2010, 39, 2007 DOI: 10.1039/B915418C

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