Liposome-mediated amplified detection of cell-secreted matrix metalloproteinase-9

Jayati Banerjee; Andrea J. Hanson; Erin K. Nyren-Erickson; Bratati Ganguli; Anil Wagh; Wallace W. Muhonen; Benedict Law; John B. Shabb; D. K. Srivastava; Sanku Mallik

doi:10.1039/B926554F

Liposome-mediated amplified detection ofcell-secreted matrix metalloproteinase-9†

Jayati Banerjee,^a Andrea J. Hanson,^a Erin K. Nyren-Erickson,^a Bratati Ganguli,^b Anil Wagh,^a Wallace W. Muhonen,^c Benedict Law,^a John B. Shabb,^c D. K. Srivastava^b and Sanku Mallik*^a

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^a Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58105, USA
E-mail: Sanku.Mallik@ndsu.edu
Fax: +1-701-231-8333
Tel: +1-701-231-7888

^b Department of Chemistry, Biochemistry and Molecular Biology, North Dakota State University, Fargo, North Dakota 58105, USA

^c Department of Biochemistry and Molecular Biology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota 58202, USA

Abstract

A liposome-based amplified detection system is presented for the cancer cell secreted pathogenic enzyme matrix metalloproteinase-9 which does not require the use of biological antibodies.

Chemical Communications

Liposome-mediated amplified detection ofcell-secreted matrix metalloproteinase-9†

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Liposome-mediated amplified detection of cell-secreted matrix metalloproteinase-9

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