Issue 1, 2011
From the journal:

Analyst

Protease sensing with nanoparticle based platforms

Katharina Welser,ab   Rosemary Adsley,ab   Bernadette M. Moore,b   Weng C. Chan*a  and  Jonathan W. Aylott*b  

* Corresponding authors

a School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, UK
E-mail: weng.chan@nottingham.ac.uk

b School of Pharmacy, Boots Science Building, University of Nottingham, University Park, Nottingham, UK
E-mail: jon.aylott@nottingham.ac.uk

Abstract

Nanoparticulate systems in various unique configurations are highly effective at detecting protease activity both in vivo and in vitro. In this article, we have summarised the conventional modern methods for monitoring protease activity, and critically appraised recent advances in protease-responsive nanosensors.

Graphical abstract: Protease sensing with nanoparticle based platforms

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Article information

DOI
https://doi.org/10.1039/C0AN00429D
Article type
Critical Review
Submitted
21 Jun 2010
Accepted
24 Aug 2010
First published
28 Sep 2010

Analyst, 2011,136, 29-41

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Protease sensing with nanoparticle based platforms

K. Welser, R. Adsley, B. M. Moore, W. C. Chan and J. W. Aylott, Analyst, 2011, 136, 29 DOI: 10.1039/C0AN00429D

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