Silver triflate and N-heterocyclic carbene co-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde

Abstract

A highly efficient silver triflate and N-heterocyclic carbene co-catalyzed three-component reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde is described, which gives rise to the 2-amino-1,2-dihydroisoquinolines in good yield.