Issue 36, 2010
From the journal:

Chemical Communications

Construction of 3-oxyindoles via hypervalent iodine mediated tandem cyclization–acetoxylation of o-acyl anilines†

Yi Suna  and  Renhua Fan*a  

* Corresponding authors

a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China
E-mail: rhfan@fudan.edu.cn
Fax: 86-21-6510-2412
Tel: 86-21-6564-2019

Abstract

An efficient tandem cyclization–acetoxylation of o-acyl anilines mediated by the combination of iodobenzene diacetate with tetrabutylammonium iodide provides a new convenient and useful route to 2-acetoxy indolin-3-ones, which are ready to be converted into other 2-substituted 3-oxyindole derivatives.

Graphical abstract: Construction of 3-oxyindoles via hypervalent iodine mediated tandem cyclization–acetoxylation of o-acyl anilines

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Article information

DOI
https://doi.org/10.1039/C0CC01911A
Article type
Communication
Submitted
16 Jun 2010
Accepted
06 Jul 2010
First published
23 Aug 2010

Chem. Commun., 2010,46, 6834-6836

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Construction of 3-oxyindoles via hypervalent iodine mediated tandem cyclization–acetoxylation of o-acyl anilines

Y. Sun and R. Fan, Chem. Commun., 2010, 46, 6834 DOI: 10.1039/C0CC01911A

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