Issue 1, 2011

Isothermal detection of RNA with restriction endonucleases

Abstract

Herein, we demonstrate how to detect nucleic acids that do not contain restriction endonuclease recognition sites with restriction endonucleases. We show that the topology of DNA probes used in this detection strategy remarkably affects the efficiency of RNA/DNA detection.

Graphical abstract: Isothermal detection of RNA with restriction endonucleases

Supplementary files

Article information

Article type
Communication
Submitted
29 Jun 2010
Accepted
13 Sep 2010
First published
01 Oct 2010

Chem. Commun., 2011,47, 200-202

Isothermal detection of RNA with restriction endonucleases

L. Yan, S. Nakayama, S. Yitbarek, I. Greenfield and H. O. Sintim, Chem. Commun., 2011, 47, 200 DOI: 10.1039/C0CC02208J

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