Issue 43, 2010

Enhancement of antimicrobial activity by synthetic ion channel synergy

Abstract

Hydraphile synthetic ion channels were found to enhance the cytotoxicity to E. coli and B. subtilis of erythromycin, kanamycin, rifampicin, and tetracycline when co-administered with the antibiotic at sublethal concentrations of channel.

Graphical abstract: Enhancement of antimicrobial activity by synthetic ion channel synergy

Article information

Article type
Communication
Submitted
09 Aug 2010
Accepted
24 Sep 2010
First published
08 Oct 2010

Chem. Commun., 2010,46, 8166-8167

Enhancement of antimicrobial activity by synthetic ion channel synergy

J. L. Atkins, M. B. Patel, Z. Cusumano and G. W. Gokel, Chem. Commun., 2010, 46, 8166 DOI: 10.1039/C0CC03138K

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