Issue 6, 2011

Amplification of G-quadruplex DNAzymes using PCR-like temperature cycles for specific nucleic acid and single nucleotide polymorphism detection

Abstract

A nucleic acid sensor, based on the amplified formation of G-quadruplex DNAzymes by polymerase chain reaction (PCR)-like temperature cycles, was developed. This “turn-on” process allowed effective detection of specific nucleic acid targets and identification of single nucleotide polymorphisms (SNPs).

Graphical abstract: Amplification of G-quadruplex DNAzymes using PCR-like temperature cycles for specific nucleic acid and single nucleotide polymorphism detection

Supplementary files

Article information

Article type
Communication
Submitted
01 Oct 2010
Accepted
04 Nov 2010
First published
29 Nov 2010

Chem. Commun., 2011,47, 1728-1730

Amplification of G-quadruplex DNAzymes using PCR-like temperature cycles for specific nucleic acid and single nucleotide polymorphism detection

N. Wang, D. Kong and H. Shen, Chem. Commun., 2011, 47, 1728 DOI: 10.1039/C0CC04182C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements