Issue 12, 2011

The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction

Abstract

The first chemical incorporation of the boronic acid group into DNA using a copper-free click reagent was reported. Compared with the PCR-based method, this approach allows for site-specific incorporation and synthesis on a larger scale.

Graphical abstract: The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction

Supplementary files

Article information

Article type
Communication
Submitted
21 Oct 2010
Accepted
17 Jan 2011
First published
08 Feb 2011

Chem. Commun., 2011,47, 3598-3600

The first chemical synthesis of boronic acid-modified DNA through a copper-free click reaction

C. Dai, L. Wang, J. Sheng, H. Peng, A. B. Draganov, Z. Huang and B. Wang, Chem. Commun., 2011, 47, 3598 DOI: 10.1039/C0CC04546B

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