A pH-driven DNA nanoswitch for responsive controlled release

Linfeng Chen; Jiancheng Di; Changyan Cao; Yong Zhao; Ying Ma; Jia Luo; Yongqiang Wen; Weiguo Song; Yanlin Song; Lei Jiang

doi:10.1039/C0CC04765A

A pH-driven DNA nanoswitch for responsive controlled release†

Linfeng Chen,^a Jiancheng Di,^b Changyan Cao,^a Yong Zhao,^a Ying Ma,^a Jia Luo,^a Yongqiang Wen,*^a Weiguo Song,^a Yanlin Song*^a and Lei Jiang^a

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* Corresponding authors

^a Beijing National Laboratory for Molecular Sciences (BNLMS), Key Lab of Organic Solids, Laboratory of New Materials, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: ylsong@iccas.ac.cn, wyq_wen@iccas.ac.cn

^b State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China

Abstract

An intelligent pH-responsive carrier and release system based on DNA nanoswitch-controlled organization of gold nanoparticles (AuNPs) attached to mesoporous silica (MS) has been designed and demonstrated.

Chemical Communications

A pH-driven DNA nanoswitch for responsive controlled release†

Abstract

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A pH-driven DNA nanoswitch for responsive controlled release

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