Issue 8, 2011

Interaction of peptides with graphene oxide and its application for real-time monitoring of protease activity

Abstract

We have developed a novel graphene-based biosensing platform using peptides as probe biomolecules, and demonstrated its feasibility in the application of real-time monitoring of protease activity based on FRET between GO and dye-labeled peptides. This assay allows the rapid and accurate determination of enzyme kinetic parameters as well as inhibition constants.

Graphical abstract: Interaction of peptides with graphene oxide and its application for real-time monitoring of protease activity

Supplementary files

Article information

Article type
Communication
Submitted
10 Nov 2010
Accepted
26 Nov 2010
First published
16 Dec 2010

Chem. Commun., 2011,47, 2399-2401

Interaction of peptides with graphene oxide and its application for real-time monitoring of protease activity

M. Zhang, B. Yin, X. Wang and B. Ye, Chem. Commun., 2011, 47, 2399 DOI: 10.1039/C0CC04887A

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