Issue 2, 2011
From the journal:

Chemical Science

Structurally simple lipid bilayer transport agents for chloride and bicarbonate†

Natalie J. Andrews,a   Cally J. E. Haynes,a   Mark E. Light,a   Stephen J. Moore,a   Christine C. Tong,‡a   Jeffery T. Davis,b   William A. Harrell Jr.b  and  Philip A. Gale*a  

* Corresponding authors

a School of Chemistry, University of Southampton, Southampton, UK
E-mail: philip.gale@soton.ac.uk
Fax: (+44) 23 0859 6805

b Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, USA

Abstract

A new series of structurally simple compounds containing thiourea groups have been shown by a combination of ion-selective electrode and 13C NMR techniques to be potent chloride-bicarbonate exchange agents that function at low concentration in POPC and POPC/cholesterol membranes.

Graphical abstract: Structurally simple lipid bilayer transport agents for chloride and bicarbonate

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Article information

DOI
https://doi.org/10.1039/C0SC00503G
Article type
Edge Article
Submitted
26 Sep 2010
Accepted
21 Oct 2010
First published
23 Nov 2010

Chem. Sci., 2011,2, 256-260

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Structurally simple lipid bilayer transport agents for chloride and bicarbonate

N. J. Andrews, C. J. E. Haynes, M. E. Light, S. J. Moore, C. C. Tong, J. T. Davis, W. A. Harrell Jr. and P. A. Gale, Chem. Sci., 2011, 2, 256 DOI: 10.1039/C0SC00503G

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