Issue 18, 2011

Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents

Abstract

Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited tumor cell proliferation by interfering into regulatory pathways of the cell cycleviaapoptosis.

Graphical abstract: Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents

Supplementary files

Article information

Article type
Communication
Submitted
10 Jan 2011
Accepted
14 Mar 2011
First published
30 Mar 2011

Chem. Commun., 2011,47, 5184-5186

Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents

V. Vajpayee, Y. J. Yang, S. C. Kang, H. Kim, I. S. Kim, M. Wang, P. J. Stang and K. Chi, Chem. Commun., 2011, 47, 5184 DOI: 10.1039/C1CC10167F

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