Issue 15, 2011

A novel zwitterionic HILIC stationary phase based on “thiol-ene” click chemistry between cysteine and vinyl silica

Abstract

A novel zwitterionic stationary phase with high hydrophilicity was facilely synthesized based on the “thiol-ene” click reaction between cysteine and vinyl silica, which exhibited great potential in the separation of oligosaccharides, peptides and basic compounds, as well as in the enrichment of glycopeptides.

Graphical abstract: A novel zwitterionic HILIC stationary phase based on “thiol-ene” click chemistry between cysteine and vinyl silica

Article information

Article type
Communication
Submitted
21 Jan 2011
Accepted
22 Feb 2011
First published
14 Mar 2011

Chem. Commun., 2011,47, 4550-4552

A novel zwitterionic HILIC stationary phase based on “thiol-ene” click chemistry between cysteine and vinyl silica

A. Shen, Z. Guo, L. Yu, L. Cao and X. Liang, Chem. Commun., 2011, 47, 4550 DOI: 10.1039/C1CC10421G

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