Issue 17, 2011
From the journal:

Chemical Communications

Chiral (thio)phosphorodiamides as excellent hydrogen bond donor catalysts in the asymmetric Michael addition of 2-hydroxy-1,4-naphthoquione to nitroolefins†

Ronghua Wu,a   Xufang Chang,a   Aidang Lu,a   Youming Wang,*a   Guiping Wu,a   Haibin Song,a   Zhenghong Zhou*a  and  Chuchi Tanga  

* Corresponding authors

a State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China
E-mail: z.h.zhou@nankai.edu.cn

Abstract

A novel type of bidentate hydrogen bond donor catalysts based on (thio)phosphorodiamides catalophore has been developed for the asymmetric Michael addition of 2-hydroxy-1,4-naphthoquione to nitroolefins, affording the corresponding adducts in high yields with excellent level of enantioselectivities (97– >99% ee).

Graphical abstract: Chiral (thio)phosphorodiamides as excellent hydrogen bond donor catalysts in the asymmetric Michael addition of 2-hydroxy-1,4-naphthoquione to nitroolefins

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C1CC10797F
Article type
Communication
Submitted
11 Feb 2011
Accepted
10 Mar 2011
First published
24 Mar 2011

Chem. Commun., 2011,47, 5034-5036

Permissions

Request permissions

Chiral (thio)phosphorodiamides as excellent hydrogen bond donor catalysts in the asymmetric Michael addition of 2-hydroxy-1,4-naphthoquione to nitroolefins

R. Wu, X. Chang, A. Lu, Y. Wang, G. Wu, H. Song, Z. Zhou and C. Tang, Chem. Commun., 2011, 47, 5034 DOI: 10.1039/C1CC10797F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements