Issue 26, 2011

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

Abstract

Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO2, and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.

Graphical abstract: Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

Supplementary files

Article information

Article type
Communication
Submitted
01 Apr 2011
Accepted
04 May 2011
First published
02 Jun 2011

Chem. Commun., 2011,47, 7347-7349

Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells

D. G. Smith, G. Law, B. S. Murray, R. Pal, D. Parker and K. Wong, Chem. Commun., 2011, 47, 7347 DOI: 10.1039/C1CC11853F

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