One pot iridium-catalyzed asymmetrical double allylations of sodium sulfide: a fast and economic way to construct chiral C2-symmetric bis(1-substituted-allyl)sulfane

Abstract

One pot asymmetrical double allylations of sodium sulfide catalyzed by an iridium complex along with a combination of caesium fluoride and water in dichloromethane have been realized and the double allylation products with two C–S bond chiral centers were obtained in 67–99% yields with b/l 81/19–99/1, dr 85/15–99/1, and 96–99% ee.