Issue 27, 2011

Label-free fluorescent detection of Cu(ii) ions based on DNA cleavage-dependent graphene-quenched DNAzymes

Abstract

We developed a novel and general methodology to design a label-free fluorescent Cu(II) sensor based on internal DNA cleavage and an extrinsic fluorophore in a graphene/DNAzymes complex with high sensitivity and selectivity.

Graphical abstract: Label-free fluorescent detection of Cu(ii) ions based on DNA cleavage-dependent graphene-quenched DNAzymes

Supplementary files

Article information

Article type
Communication
Submitted
08 Apr 2011
Accepted
28 Apr 2011
First published
18 May 2011

Chem. Commun., 2011,47, 7749-7751

Label-free fluorescent detection of Cu(II) ions based on DNA cleavage-dependent graphene-quenched DNAzymes

M. Liu, H. Zhao, S. Chen, H. Yu, Y. Zhang and X. Quan, Chem. Commun., 2011, 47, 7749 DOI: 10.1039/C1CC12006A

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