Issue 28, 2011
From the journal:

Chemical Communications

Two-photon induced responsive f–f emissive detection of Cyclin A with a europium-chelating peptide†

Hoi-Kwan Kong,a   Frances L Chadbourne,b   Ga-Lai Law,b   Hongguang Li,c   Hoi-Lam Tam,e   Steven L Cobb,*b   Chi-Kong Lau,*d   Chi-Sing Lee*c  and  Ka-Leung Wong*a  

* Corresponding authors

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR
E-mail: klwong@hkbu.edu.hk
Tel: +852-34112370

b Department of Chemistry, Durham University, Durham, UK
E-mail: s.l.cobb@durham.ac.uk
Tel: +44 191 33 42086

c Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen University Town, Xili, Shenzhen 518055, China
E-mail: lizc@szpku.edu.cn
Tel: +86 2603 2701

d School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR
E-mail: tcklau@cuhk.edu.hk

e Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR

Abstract

Responsive linear and two-photon induced europium emissive probes have been synthesised with a tailor made peptide for the detection of Cyclin A, the hypersensitive Eu emission (Eu-2) gave the real time signalling and also enhanced the two-photon absorption cross section from 12 GM to 68 GM after Cyclin A binding.

Graphical abstract: Two-photon induced responsive f–f emissive detection of Cyclin A with a europium-chelating peptide

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Article information

DOI
https://doi.org/10.1039/C1CC12811F
Article type
Communication
Submitted
13 May 2011
Accepted
03 Jun 2011
First published
16 Jun 2011

Chem. Commun., 2011,47, 8052-8054

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Two-photon induced responsive f–f emissive detection of Cyclin A with a europium-chelating peptide

H. Kong, F. L. Chadbourne, G. Law, H. Li, H. Tam, S. L. Cobb, C. Lau, C. Lee and K. Wong, Chem. Commun., 2011, 47, 8052 DOI: 10.1039/C1CC12811F

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